Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.47 |
| ▸ | HTR3B | O95264 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093970 | 0.85 | PNMT (0.56) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29574711 | 0.85 | — | — | |
| SCHEMBL94762 | 0.85 | — | — | |
| SCHEMBL3300276 | 0.85 | PNMT (0.65) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10786326 | 0.85 | PDE4B (0.52) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11796800 | 0.84 | ESR1 (0.56) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11576495 | 0.83 | TSHR (0.52) | LTA4HTSHRDAO | |
| SCHEMBL3301781 | 0.83 | PNMT (0.58) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8993096 | 0.82 | PNMT (0.52) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| Ammonia Solution, Strong SCHEMBL18010559 | 0.81 | PNMT (0.56) | PNMTHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |