Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29288338 | 0.68 | NR1H4 (0.47) | USP14MRGPRX4 | |
| SCHEMBL8993104 | 0.68 | IDO1 (0.35) | FFAR4USP14IDO1TACR1 | |
| SCHEMBL30079928 | 0.66 | USP14 (0.35) | USP14IDO1TACR1 | |
| SCHEMBL2140588 | 0.66 | BACE1 (0.37) | USP14MAOBIDO1TACR1 | |
| SCHEMBL30132937 | 0.66 | USP14 (0.36) | USP14 | |
| SCHEMBL1166722 | 0.65 | MRGPRX4 (0.38) | USP14MRGPRX4TACR1 | |
| SCHEMBL30079875 | 0.65 | USP14 (0.35) | USP14TACR1 | |
| SCHEMBL22275629 | 0.65 | USP14 (0.35) | USP14TACR1 | |
| SCHEMBL8993025 | 0.64 | USP14 (0.34) | FFAR4USP14 | |
| SCHEMBL5454226 | 0.64 | SKP2 (0.44) | USP14IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |