Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993113 | 0.84 | CASR (0.51) | CASRTAAR1LMNAHTTAOC3 | |
| SCHEMBL10290007 | 0.83 | CASR (0.53) | CASRTAAR1AOC3L3MBTL1 | |
| SCHEMBL10707052 | 0.81 | CASR (0.57) | CASRTAAR1AOC3L3MBTL1 | |
| SCHEMBL8993157 | 0.81 | CASR (0.48) | CASRTAAR1LMNAHTTAOC3 | |
| SCHEMBL23621916 | 0.79 | CASR (0.52) | CASRTAAR1MEN1KMT2A | |
| SCHEMBL2997237 | 0.77 | TAAR1 (0.40) | TAAR1AOC3MEN1KMT2ATTR | |
| SCHEMBL8365761 | 0.75 | LMNA (0.56) | TAAR1LMNAHTTTTR | |
| SCHEMBL28310868 | 0.74 | AOC3 (0.45) | CASRLMNAAOC3L3MBTL1KMT2A | |
| SCHEMBL29484318 | 0.74 | TAAR1 (0.60) | TAAR1HTTAOC3TTR | |
| SCHEMBL228859 | 0.74 | TAAR1 (0.60) | TAAR1HTTAOC3TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |