SCHEMBL8993231

SCHEMBL8993231

C=C(C)C(=O)OC(Cl)CCO

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1130721 0.84 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL8651323 0.84 ALDH1A1 (0.43) TSHRALDH1A1THRB
SCHEMBL10204589 0.83 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL8979530 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL27991542 0.81 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL203066 0.79 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL3981743 0.79 TSHR (0.49) TSHRALDH1A1
SCHEMBL489136 0.79 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL11721506 0.79 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL1951992 0.79 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0371822-B1 Copolymers of 3-methacryloyloxy-2-hydroxypropyl trimethylammonium chloride monomer and vinyl monomer S N F (FR) 1996-08-14 EP disclosed