SCHEMBL8993281

SCHEMBL8993281

OCCCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.60
DRD2 P14416 2/20 0.44
DRD4 P21917 2/20 0.44
DRD3 P35462 2/20 0.44
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HTR7 P34969 1/20 0.39
HTR2B P41595 1/20 0.39
PGR P06401 2/20 0.35
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993405 0.95 PNMT (0.58) PNMTDRD2DRD4DRD3NPC1
SCHEMBL1567178 0.90 PNMT (0.64) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6674911 0.90 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6675794 0.90 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6674622 0.88 PNMT (0.66) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7605895 0.88 PNMT (0.66) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6676505 0.88 PNMT (0.66) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7604911 0.88 PNMT (0.66) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL5352652 0.86 PNMT (0.64) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL5353731 0.86 PNMT (0.64) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102964767-A Fluorescent conjugated polymer and magnetic nanoparticle composite material and preparation method thereof UNIV NANJING POSTS & TELECOMM 2013-03-13 CN claimed
CN-101864042-B Water-soluble fluorine-containing grafting conjugated polymer and preparation method and application method thereof UNIV NANJING POSTS & TELECOMM 2012-10-24 CN claimed
CN-101864042-A Water-soluble fluorine-containing grafting conjugated polymer and preparation method and application method thereof UNIV NANJING POSTS & TELECOMM 2010-10-20 CN claimed
CN-102964767-A Fluorescent conjugated polymer and magnetic nanoparticle composite material and preparation method thereof UNIV NANJING POSTS & TELECOMM 2013-03-13 CN disclosed
CN-101864042-B Water-soluble fluorine-containing grafting conjugated polymer and preparation method and application method thereof UNIV NANJING POSTS & TELECOMM 2012-10-24 CN disclosed
CN-101864042-A Water-soluble fluorine-containing grafting conjugated polymer and preparation method and application method thereof UNIV NANJING POSTS & TELECOMM 2010-10-20 CN disclosed
CN-100358933-C Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2008-01-02 CN disclosed
CN-1827664-A Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2006-09-06 CN disclosed
CN-1594314-A Fluorene based water soluble conjugated polymer and process for preparing same UNIV FUDAN (CN) 2005-03-16 CN disclosed
US-5519043-A ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE SCIOS NOVA INC. (US) 1996-05-21 US disclosed