⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993295 | 0.81 | — | — | |
| SCHEMBL11399371 | 0.71 | — | — | |
| SCHEMBL5033001 | 0.66 | — | — | |
| SCHEMBL4956261 | 0.66 | — | — | |
| SCHEMBL30457826 | 0.66 | LMNA (0.33) | — | |
| SCHEMBL3969262 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL3963502 | 0.61 | — | — | |
| SCHEMBL30407253 | 0.61 | — | — | |
| SCHEMBL28890190 | 0.61 | — | — | |
| SCHEMBL629380 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3518935-A1 | THERAPEUTIC COMPOSITIONS FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | Gilead Sciences, Inc. (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3341373-A1 | DEUTERATED TOLL-LIKE RECEPTOR MODULATORS | Gilead Sciences, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2018064071-A1 | THERAPEUTIC COMPOSITIONS FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | GILEAD SCIENCES, INC. (US) | 2018-04-05 | — | — | WO | disclosed |
| WO-2017035230-A1 | DEUTERATED TOLL-LIKE RECEPTOR MODULATORS | GILEAD SCIENCES, INC. (US) | 2017-03-02 | — | — | WO | disclosed |
| US-5504077-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |