Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359473 | 0.83 | KMT2A (0.65) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL8846878 | 0.73 | SMN1; SMN2 (0.53) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL6555228 | 0.73 | SMN1; SMN2 (0.53) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL8846872 | 0.73 | SMN1; SMN2 (0.53) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL8993466 | 0.72 | SMN1; SMN2 (0.52) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL6544579 | 0.72 | MAPT (0.49) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL22721829 | 0.67 | MEN1 (0.58) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL29299973 | 0.66 | MEN1 (0.57) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL29299975 | 0.66 | MEN1 (0.57) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL9252504 | 0.64 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5399708-A | Cholecystokinin and gastrin antagonists; gastrointestinal and central nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |