Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846872 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| SCHEMBL8846878 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| SCHEMBL6555228 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8993466 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| SCHEMBL8993520 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| SCHEMBL12474357 | 0.69 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| SCHEMBL22559985 | 0.67 | SLC6A3 (0.54) | SMN1; SMN2SLC6A3SLC6A2 | |
| Naphthalene SCHEMBL6635288 | 0.66 | BRPF1 (0.42) | GAAMAPTSLC6A3ALDH1A1SLC6A2 | |
| SCHEMBL10843954 | 0.65 | SMN1; SMN2 (0.65) | SMN1; SMN2GAAMAPTSLC6A3ALDH1A1 | |
| SCHEMBL8993492 | 0.64 | MEN1 (0.59) | SMN1; SMN2GAAMAPTALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399708-A | Cholecystokinin and gastrin antagonists; gastrointestinal and central nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |