Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212242 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8870727 | 0.83 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL8654013 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL8871135 | 0.76 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8654783 | 0.75 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5698518 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6818292 | 0.73 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL10078922 | 0.71 | HPGD (0.53) | PTGS2 | |
| SCHEMBL6243674 | 0.71 | KCNH2 (0.50) | PTGS2 | |
| SCHEMBL8654725 | 0.70 | PTGS2 (0.62) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |