Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521548 | 0.95 | TSHR (0.43) | TSHRHPGDTHRBTHRACA1 | |
| SCHEMBL500591 | 0.94 | TSHR (0.42) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL11674285 | 0.94 | TSHR (0.42) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL499596 | 0.94 | TSHR (0.42) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL499683 | 0.94 | TSHR (0.42) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL927084 | 0.90 | TSHR (0.39) | TSHRHPGDTHRBTHRAALDH1A1 | |
| SCHEMBL5247453 | 0.85 | TSHR (0.49) | TSHRHPGDTHRBTHRACTSK | |
| SCHEMBL11424256 | 0.85 | TSHR (0.37) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11279407 | 0.84 | TSHR (0.42) | TSHRHPGDTHRBTHRACA1 | |
| SCHEMBL14956997 | 0.84 | TSHR (0.42) | TSHRHPGDTHRBTHRACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943596-A | Viscosity index improver and preparation method and application thereof | 一汽解放汽车有限公司 | 2022-01-18 | — | — | CN | disclosed |
| US-5578678-A | N-VINYLCARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |