Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | TPI1 | P60174 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL19458367 | 1.00 | FDPS (0.67) | FDPSBLMTDP1CA4TPI1 | |
| Pyrophosphoric Acid SCHEMBL229477 | 1.00 | FDPS (0.67) | FDPSBLMTDP1CA4TPI1 | |
| Pyrophosphoric Acid SCHEMBL2407700 | 1.00 | FDPS (0.67) | FDPSBLMTDP1CA4TPI1 | |
| Triphosphate SCHEMBL122712 | 0.88 | FDPS (0.50) | FDPSBLMTDP1CA4TPI1 | |
| Triphosphate SCHEMBL8023890 | 0.88 | FDPS (0.50) | FDPSBLMTDP1CA4TPI1 | |
| Guanidine SCHEMBL32685203 | 0.85 | FDPS (0.47) | FDPSBLMTDP1CA4TPI1 | |
| Pyrophosphoric Acid SCHEMBL19458364 | 0.83 | FDPS (0.53) | FDPSBLMTDP1CA4 | |
| Pyrophosphoric Acid SCHEMBL4147800 | 0.83 | TDP1 (0.71) | FDPSBLMTDP1CA4TPI1 | |
| Pyrophosphoric Acid SCHEMBL8416891 | 0.82 | FDPS (0.83) | FDPSBLMTDP1CA4TPI1 | |
| Pyrophosphoric Acid SCHEMBL10770702 | 0.82 | FDPS (0.83) | FDPSBLMTDP1CA4TPI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338923-B1 | Polyurethane with a biocidal polyuric material as comonomer | OBERWALDER SEBASTIAN (DE) | 2017-10-18 | — | — | EP | claimed |
| CN-109963885-B | Guanidine diphosphate and guanidine polyphosphate ligands and group IV metal catalysts produced therefrom | 陶氏环球技术有限责任公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-0725065-A2 | Process for the preparation of guanidine or melamine phosphates | DSM Chemie Linz GmbH (AT) | 1996-08-07 | — | — | EP | disclosed |