SCHEMBL8993715

SCHEMBL8993715

CC(C)(C)OC(=O)N(C1CCCN(C(Cc2ccc(C#N)cc2)C(=O)N2CCCCC2)C1=O)S(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.40
P2RX7 Q99572 1/20 0.39
CASR P41180 1/20 0.35
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8993751 0.79 F10 (0.57) F10F2
SCHEMBL8993731 0.71 F10 (0.60) F10
SCHEMBL8993873 0.71 FPR1 (0.41) F10P2RX7
SCHEMBL8993701 0.68 F10 (0.45) F10F2
SCHEMBL8651591 0.68 F2 (0.36) F10P2RX7F2
SCHEMBL8993762 0.67 DPP4 (0.46)
SCHEMBL8993691 0.67 F2 (0.64) F10F2
SCHEMBL10617613 0.67 FPR1 (0.47) F10P2RX7F2
SCHEMBL6952090 0.66 ADORA1 (0.46) P2RX7
SCHEMBL8993767 0.65 F2 (0.62) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489583-A FOR TREATING OR PREVENTING THROMBOSIS BASF AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed