Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234130 | 0.79 | RAD52 (0.56) | RAD52KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8265639 | 0.77 | RAD52 (0.55) | RAD52KMT2AALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8993826 | 0.77 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL6980198 | 0.74 | ELANE (0.55) | RAD52KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3713978 | 0.74 | RAD52 (0.52) | RAD52KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL15804004 | 0.74 | ELANE (0.70) | PKMRAD52KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7284088 | 0.72 | RAD52 (0.50) | RAD52KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8993820 | 0.71 | ELANE (0.52) | RAD52KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8993761 | 0.71 | RAD52 (0.47) | RAD52KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25434321 | 0.70 | RECQL (0.55) | RAD52KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489583-A | FOR TREATING OR PREVENTING THROMBOSIS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | disclosed |