Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | FGB | P02675 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993832 | 0.72 | CCR1 (0.43) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL8993821 | 0.71 | MEN1 (0.50) | L3MBTL1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL14584275 | 0.70 | CCR1 (0.61) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL11907479 | 0.70 | CCR1 (0.56) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL18788315 | 0.69 | PTPN1 (0.51) | CCR1CCR8L3MBTL1MEN1KMT2A | |
| SCHEMBL18788338 | 0.69 | CCR1 (0.51) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL344920 | 0.68 | PTPN1 (0.50) | CCR1CCR8L3MBTL1MEN1KMT2A | |
| SCHEMBL18806842 | 0.68 | CCR1 (0.54) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL18806844 | 0.68 | L3MBTL1 (0.54) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 | |
| SCHEMBL8925893 | 0.68 | TLR8 (0.43) | HSP90AA1HSP90AB1CCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550241-A | Adducts of cyclic carbonyl monomers and substituted alkens | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1996-08-27 | — | — | US | disclosed |