Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40057 | 0.88 | MEN1 (0.64) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL181768 | 0.88 | MEN1 (0.64) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL40056 | 0.88 | MEN1 (0.64) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3316718 | 0.86 | MAPT (0.52) | MAPTKMT2AMEN1ALDH1A1SLC6A1 | |
| Hydrazine SCHEMBL27951659 | 0.85 | MEN1 (0.61) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28532654 | 0.84 | HPGD (0.44) | MAPTKMT2AMEN1ALDH1A1SLC6A1 | |
| SCHEMBL30769887 | 0.84 | HPGD (0.61) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31421106 | 0.84 | HPGD (0.61) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1439980 | 0.84 | HPGD (0.61) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18391126 | 0.84 | HPGD (0.61) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |