Sugi Predict

Sugi Predict / Compounds / SCHEMBL181768

SCHEMBL181768

SCHEMBL181768

CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)O)C1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.64
▸ ALDH1A1 P00352 1/20 0.64
▸ MAPT P10636 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ HPGD P15428 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.55
▸ EPHX1 P07099 1/20 0.49
▸ HSD11B1 P28845 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ USP30 Q70CQ3 1/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ ABL1 P00519 1/20 0.44
▸ RIN1 Q13671 1/20 0.44
▸ BTK Q06187 1/20 0.44
▸ USP2 O75604 1/20 0.44
▸ PREP P48147 1/20 0.43
▸ GLS O94925 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40057 1.00 MEN1 (0.64) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL40056 1.00 MEN1 (0.64) MEN1ALDH1A1MAPTKMT2AHPGD
Hydrazine SCHEMBL27951659 0.97 MEN1 (0.61) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL18391126 0.95 HPGD (0.61) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL30769887 0.95 HPGD (0.61) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL31421106 0.95 HPGD (0.61) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL1439980 0.95 HPGD (0.61) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL3919651 0.94 HPGD (0.61) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL27963722 0.94 HPGD (0.65) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL42957 0.90 HPGD (0.62) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016029146-A1 SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE UNIVERSITY OF WASHINGTON (US) 2016-02-25 — — WO claimed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 — — US disclosed
US-12583839-B2 PD-L1 antagonist compound ADLAI NORTYE BIOPHARMA CO., LTD. (CN) 2026-03-24 — — US disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
EP-4695236-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2026-02-18 — — EP disclosed
EP-4688738-A1 HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA Atrogi AB (SE) 2026-02-11 — — EP disclosed
EP-4192833-B1 PHARMACOLOGICALLY ACTIVE HETEROCYCLIC-SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES RICHTER GEDEON NYRT (HU) 2026-01-21 — — EP disclosed
US-12492200-B2 NLRP3 modulators Birstol Myers-Squibb Company (US) 2025-12-09 — — US disclosed
US-12479821-B2 Quinoline compound and use thereof MBD Co., Ltd. (KR) 2025-11-25 — — US disclosed
US-12473293-B2 Pharmacologically active heterocyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives RICHTER GEDEON NYRT. (HU) 2025-11-18 — — US disclosed
EP-1165543-A1 PROCESS FOR PREPARING S-(R*,S*)] -$g(b) - 1- 1-OXO-3- (4-PIPERIDINYL) PROPYL] -3-PIPERIDINYL] CARBONYL] AMINO] -3- PYRIDINEPROPANOIC ACID AND DERIVATIVES Ortho-Mcneil Pharmaceutical, Inc. (US) 2002-01-02 — — EP disclosed
WO-2000056730-A1 PROCESS FOR PREPARING [S-(R*,S*)] -β -[[[1-[1-OXO-3- (4-PIPERIDINYL) PROPYL] -3-PIPERIDINYL] CARBONYL] AMINO] -3- PYRIDINEPROPANOIC ACID AND DERIVATIVES ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2000-09-28 — — WO disclosed
US-6013658-A ANIMAL GROWTH REGULATORS NOVO NORDISK A/S (DK) 2000-01-11 — — US disclosed
CN-1040432-C Spiro piperdines and homologs promote release of growth hormone MERCK & CO INC (US) 1998-10-28 — — CN disclosed
CN-1176645-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1998-03-18 — — CN disclosed
EP-0805816-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-11-12 — — EP disclosed
WO-1996032943-A1 3-SUBSTITUTED PIPERIDINES PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO., INC. (US) 1996-10-24 — — WO disclosed
US-5559128-A FOOD ANIMALS; MEDICAL DIAGNOSIS MERCK & CO., INC. (US) 1996-09-24 — — US disclosed
WO-1996022997-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1996-08-01 — — WO disclosed
CN-1092767-A Promote spiroperidol and homologue that tethelin discharges MERCK & CO INC (US) 1994-09-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479821-B2 Quinoline compound and use thereof CYP4A11, CYP7A1, CYP4B1 MEN1 4845/4885ALDH1A1 647/4885MAPT 3265/4885
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 MEN1 4640/4885ALDH1A1 217/4885MAPT 2797/4885
US-12492200-B2 NLRP3 modulators NLRP3, NLRP1, PYCARD MEN1 3090/4885ALDH1A1 864/4885MAPT 1594/4885
US-12473293-B2 Pharmacologically active heterocyclic-substituted pyrazolo[1,5-a]pyrimidine derivatives GABRA5, GABRA1, P2RX5 MEN1 3529/4885ALDH1A1 578/4885MAPT 1890/4885
US-12583839-B2 PD-L1 antagonist compound CD274, PDCD1LG2, PDCD1 MEN1 4166/4885ALDH1A1 747/4885MAPT 4182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.