Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 10/20 | 0.57 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458624 | 0.91 | SRD5A2 (0.61) | SRD5A2SRD5A1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8994112 | 0.91 | SRD5A2 (0.70) | SRD5A2SRD5A1 | |
| SCHEMBL8994109 | 0.91 | SRD5A2 (0.70) | SRD5A2SRD5A1 | |
| SCHEMBL8994120 | 0.89 | SRD5A2 (0.59) | SRD5A2SRD5A1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8994154 | 0.84 | SRD5A2 (0.53) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8994093 | 0.84 | SRD5A2 (0.62) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8994153 | 0.84 | SRD5A2 (0.57) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9392669 | 0.84 | SRD5A2 (0.66) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8158161 | 0.83 | SRD5A2 (0.81) | SRD5A2SRD5A1 | |
| SCHEMBL8158159 | 0.83 | SRD5A2 (0.81) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721460-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996003420-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA S.P.A. (IT) | 1996-02-08 | — | — | WO | disclosed |