Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 13/20 | 0.66 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.66 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994153 | 0.91 | SRD5A2 (0.57) | SRD5A2SRD5A1PSEN1PSEN2APH1B | |
| SCHEMBL8994162 | 0.86 | SRD5A2 (0.69) | SRD5A2SRD5A1 | |
| SCHEMBL8994119 | 0.85 | SRD5A2 (0.49) | SRD5A2SRD5A1PSEN1PSEN2APH1B | |
| SCHEMBL8994171 | 0.85 | SRD5A2 (0.74) | SRD5A2SRD5A1 | |
| SCHEMBL8994136 | 0.84 | SRD5A2 (0.74) | SRD5A2SRD5A1 | |
| SCHEMBL8908909 | 0.83 | SRD5A2 (0.65) | SRD5A2SRD5A1 | |
| SCHEMBL8994112 | 0.82 | SRD5A2 (0.70) | SRD5A2SRD5A1 | |
| SCHEMBL8994109 | 0.82 | SRD5A2 (0.70) | SRD5A2SRD5A1 | |
| SCHEMBL8149720 | 0.82 | SRD5A2 (0.75) | SRD5A2SRD5A1 | |
| SCHEMBL8149717 | 0.82 | SRD5A2 (0.75) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721460-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-17 | — | — | EP | claimed |
| WO-1996003420-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA S.P.A. (IT) | 1996-02-08 | — | — | WO | claimed |
| EP-0721460-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996003420-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA S.P.A. (IT) | 1996-02-08 | — | — | WO | disclosed |