Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | SHBG | P04278 | 2/20 | 0.60 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994147 | 1.00 | SRD5A2 (0.62) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL8634489 | 0.89 | SRD5A2 (0.75) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL8777097 | 0.84 | SMN1; SMN2 (0.64) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL9110297 | 0.84 | SMN1; SMN2 (0.64) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL8064125 | 0.82 | SRD5A2 (0.64) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL8064116 | 0.82 | SRD5A2 (0.64) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL14117502 | 0.82 | SRD5A2 (0.73) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL4254061 | 0.82 | SRD5A2 (0.73) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL2640199 | 0.81 | SRD5A2 (0.63) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL2640197 | 0.81 | SRD5A2 (0.63) | SRD5A2ALDH1A1CYP3A4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721460-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996003420-A1 | 3-CARBOXYSTEROIDS WITH A FLUORINATED SIDE CHAIN | PHARMACIA S.P.A. (IT) | 1996-02-08 | — | — | WO | disclosed |