Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25986534 | 1.00 | ESR2 (0.54) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL83852 | 0.93 | CA1 (0.61) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL25986528 | 0.93 | CA1 (0.61) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL10112753 | 0.93 | CA1 (0.61) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL12761856 | 0.87 | ACHE (0.54) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL13344241 | 0.87 | ACHE (0.54) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL10044097 | 0.87 | ACHE (0.54) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL12576165 | 0.86 | CA1 (0.52) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL2608411 | 0.86 | MAPT (0.58) | ESR2CA1CA2CA7CA9 | |
| SCHEMBL16281499 | 0.86 | MAPT (0.58) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604056-B1 | Bis[4'-(4-hydroxyphenyl)-phenyl]alkanes and polycarbonates prepared therefrom | GEN ELECTRIC (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0604056-A2 | Bis[4'-(4-hydroxyphenyl)-phenyl]alkanes and polycarbonates prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5319149-A | Bis[4'-(4-hydroxyphenyl)-phenyl]alkanes and polycarbonates prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5281689-A | Polycarbonate from bis[4'-(4-hydroxyphenyl)-phenyl]alkanes | GENERAL ELECTRIC COMPANY (US) | 1994-01-25 | — | — | US | disclosed |