Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496800 | 1.00 | TSHR (0.56) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL4619478 | 0.92 | TSHR (0.62) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL6480727 | 0.92 | TSHR (0.62) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL117951 | 0.92 | TSHR (0.62) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL5010945 | 0.92 | AR (0.56) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL14173946 | 0.91 | TSHR (0.48) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL14173742 | 0.89 | TSHR (0.47) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL14173867 | 0.87 | SMN1; SMN2 (0.45) | TSHRMAPK1LMNAMAPTHTT | |
| Bicarbonate SCHEMBL27926288 | 0.87 | TSHR (0.57) | TSHRMAPK1LMNAMAPTHTT | |
| SCHEMBL14173983 | 0.87 | MAPT (0.46) | TSHRMAPK1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501912-B1 | Methyldioxolane | CIBA GEIGY AG (CH) | 1996-08-14 | — | — | EP | disclosed |
| US-5478958-A | Stereoselective acetalization catalyst | CIBA-GEIGY CORPORATION (US) | 1995-12-26 | — | — | US | disclosed |
| US-5384416-A | Stereospecific insecticides | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5280041-A | Such as 4-((4-phenoxyphenoxy)methyl)dioxolan | CIBA-GEIGY CORPORATION (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0501912-A1 | Methyldioxolane | CIBA-GEIGY AG (CH) | 1992-09-02 | — | — | EP | disclosed |