Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228324 | 0.93 | AR (0.61) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL8994531 | 0.92 | TSHR (0.56) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL1496800 | 0.92 | TSHR (0.56) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL15500156 | 0.92 | PTGS1 (0.54) | ARTSHRMAPK1MEN1KMT2A | |
| SCHEMBL14901498 | 0.91 | AR (0.69) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL9835510 | 0.91 | AR (0.49) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL8811629 | 0.87 | AR (0.56) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL11658489 | 0.86 | AR (0.78) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL11247517 | 0.85 | PTGS1 (0.59) | ARTSHRMAPK1MAPTLMNA | |
| SCHEMBL43535 | 0.85 | PTGS1 (0.59) | ARTSHRMAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669030-B2 | Electrophotographic photoreceptor, and image forming method and apparatus using the same | RICOH COMPANY, LIMITED (JP) | 2014-03-11 | — | — | US | disclosed |
| US-8669030-B2 | Electrophotographic photoreceptor, and image forming method and apparatus using the same | RICOH COMPANY, LIMITED (JP) | 2014-03-11 | — | — | US | disclosed |
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-02 | — | — | US | disclosed |
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-02 | — | — | US | disclosed |
| US-20080138725-A1 | Electrophotographic photoreceptor, and image forming method and apparatus using the same | RICOH COMPANY LIMITED (JP) | 2008-06-12 | — | — | US | disclosed |
| US-20080138725-A1 | Electrophotographic photoreceptor, and image forming method and apparatus using the same | RICOH COMPANY LIMITED (JP) | 2008-06-12 | — | — | US | disclosed |
| US-5356965-A | Containing halogen-free aldehyde or acetal aromatic sulfonic acid salts; nondripping | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| US-4144209-A | Resin latex compositions | JOHNSON & JOHNSON (US) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | SHBG, KLK3, HSD17B11 | AR 4/4885TSHR 2717/4885MAPK1 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.