Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763519 | 1.00 | MEN1 (0.56) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL5742769 | 0.90 | ACE (0.60) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL5742774 | 0.90 | ACE (0.60) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL7284941 | 0.88 | MEN1 (0.54) | MEN1NPC1RAB9AKMT2AF2 | |
| SCHEMBL10100244 | 0.88 | MEN1 (0.54) | MEN1NPC1RAB9AKMT2APREP | |
| SCHEMBL10510787 | 0.85 | ACE (0.58) | MEN1NPC1RAB9AKMT2AFKBP1A | |
| SCHEMBL7330019 | 0.85 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2AACE | |
| SCHEMBL5741647 | 0.85 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2AACE | |
| SCHEMBL5741652 | 0.85 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2AACE | |
| SCHEMBL10507846 | 0.84 | ACE (0.59) | MEN1NPC1RAB9AKMT2AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537802-A2 | N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | claimed |
| US-5545657-A | 1-ALKYLOYLPYRROLIDIN-2-YLOXOALKANOIC ACIDS AND DERIVATIVES; ANTIAMNESIA AGENTS; INHIBITORS OF PROLYL ENDOPEPTIDASE; SUPPRESSION OF NEUROTRANSMITTER METABOLISM | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-08-13 | — | — | US | disclosed |