SCHEMBL8994577

SCHEMBL8994577

Cc1cc(C(CCc2ccc(O)cc2)(CCc2ccc(O)cc2)c2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 18/20 0.62
ESR2 Q92731 7/20 0.62
AR P10275 3/20 0.61
IGF1R P08069 1/20 0.49
ALOX15 P16050 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30994345 0.87 ESR1 (0.54) ESR1ESR2ARIGF1RALOX15
SCHEMBL3680857 0.87 ESR1 (0.54) ESR1ESR2ARIGF1RALOX15
SCHEMBL29499839 0.87 ESR1 (0.54) ESR1ESR2ARIGF1RALOX15
SCHEMBL30375021 0.85 ESR1 (0.53) ESR1ESR2ARIGF1RALOX15
SCHEMBL6536649 0.83 ESR1 (0.59) ESR1ESR2IGF1RALOX15
SCHEMBL19690377 0.83 ESR1 (0.59) ESR1ESR2AR
SCHEMBL29499856 0.82 ESR1 (0.53) ESR1ESR2ARIGF1RALOX15
SCHEMBL3685280 0.81 ESR1 (0.51) ESR1ESR2ARIGF1RALOX15
SCHEMBL30374847 0.81 ESR1 (0.51) ESR1ESR2ARIGF1RALOX15
SCHEMBL30374814 0.81 ESR1 (0.51) ESR1ESR2ARIGF1RALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554797-A ENHANCE PHOTOSENSITIVITY AND/OR RATE OF DEVELOPMENT OF PHOTORESISTS OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-09-10 US disclosed
US-5436098-A Multilayer element with quinone diazide, resin and aromatic hydroxy compound for relief images CIBA-GEIGY CORPORATION (US) 1995-07-25 US disclosed
US-5296330-A Resolution, amorphous CIBA-GEIGY CORP. (US) 1994-03-22 US disclosed