Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249030 | 1.00 | KDM4E (0.59) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8668029 | 0.98 | KDM4E (0.57) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1249257 | 0.87 | SMN1; SMN2 (0.53) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8668036 | 0.85 | NPC1 (0.54) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL12641829 | 0.85 | NPC1 (0.54) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2964316 | 0.85 | NPC1 (0.54) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1249910 | 0.84 | HSD17B1 (0.60) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5346655 | 0.83 | NPC1 (0.53) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL978583 | 0.83 | KDM4E (0.72) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4948373 | 0.83 | KDM4E (0.64) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513536-B1 | Cyclic acylphosphinic acid derivatives and process for their preparation | HOECHST AG (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5214179-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0513536-A2 | Cyclic acylphosphinic acid derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |