Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chalcone SCHEMBL28260009 | 0.89 | MAPT (0.88) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL9338238 | 0.85 | MAPT (0.65) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL9338230 | 0.85 | MAPT (0.65) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL3687869 | 0.84 | BCHE (0.54) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL13203405 | 0.84 | CYP1B1 (0.81) | MAPTKMT2ACYP1B1SMN1; SMN2RAB9A | |
| SCHEMBL4582427 | 0.83 | MAPT (0.88) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL3448404 | 0.83 | MAPT (0.88) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL3448406 | 0.83 | MAPT (0.88) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL482916 | 0.83 | MAPT (1.00) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 | |
| SCHEMBL482915 | 0.83 | MAPT (1.00) | MAPTKMT2ACYP1B1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651024-B1 | Method of producing polymethine dyes | MINNESOTA MINING & MFG (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0651024-A1 | Method of producing polymethine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5386058-A | Method of producing polymethine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-31 | — | — | US | disclosed |