SCHEMBL8994730

SCHEMBL8994730

CCOP(=O)(OCC)Oc1cccc(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.50
MEN1 O00255 1/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
BCHE P06276 1/20 0.47
ACHE P22303 1/20 0.47
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
PARP1 P09874 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21875954 0.93 HCRTR1 (0.48) HCRTR1MEN1POLBGAAKMT2A
SCHEMBL7772917 0.93 MEN1 (0.54) HCRTR1MEN1POLBGAAKMT2A
SCHEMBL23163313 0.85 HCRTR1 (0.59) HCRTR1POLBGAACA2CA1
SCHEMBL1727475 0.83 GAA (0.53) MEN1POLBGAAKMT2ACA2
SCHEMBL20710745 0.82 CA1 (0.62) MEN1POLBGAAKMT2ACA2
SCHEMBL11763718 0.82 HCRTR1 (0.56) HCRTR1POLBGAACA2CA1
SCHEMBL22619019 0.81 MEN1 (0.47) MEN1POLBGAAKMT2ACA2
SCHEMBL27822413 0.81 POLB (0.47) MEN1POLBGAAKMT2ACA2
Phosphoric Acid Diethyl Ester Phenyl Ester SCHEMBL133234 0.80 CA1 (0.59) MEN1POLBGAAKMT2ACA2
SCHEMBL20710747 0.79 PKM (0.53) POLBCA2CA1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496769-B A kind of 2-[2-(3-methoxyl group-phenyl)-ethyl] synthetic method of-phenol Wan Hui Pharmaceutical (Anhui) Co., Ltd. (CN) 2016-05-11 CN claimed
EP-3647315-B9 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF VIVAVISION BIOTECH LTD (CN) 2025-06-04 EP disclosed
EP-3647315-B1 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF VIVAVISION BIOTECH LTD (CN) 2024-11-20 EP disclosed
US-11325929-B2 Phosphorus-containing compound and preparation and use thereof VIVAVISIONSHANGHAILTD (CN) 2022-05-10 US disclosed
CN-109134533-B Phosphorus-containing compound and preparation and application thereof 维眸生物科技(上海)有限公司 2020-08-11 CN disclosed
EP-3647315-A1 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF Vivavisionshanghailtd (CN) 2020-05-06 EP disclosed
US-20200131206-A1 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF VIVAVISIONSHANGHAILTD (CN) 2020-04-30 US disclosed
CN-109134533-A A kind of phosphorus-containing compound and its preparation and application 维眸生物科技(上海)有限公司 2019-01-04 CN disclosed
CN-104496769-B A kind of 2-[2-(3-methoxyl group-phenyl)-ethyl] synthetic method of-phenol Wan Hui Pharmaceutical (Anhui) Co., Ltd. (CN) 2016-05-11 CN disclosed
CN-104496769-B A kind of 2-[2-(3-methoxyl group-phenyl)-ethyl] synthetic method of-phenol Wan Hui Pharmaceutical (Anhui) Co., Ltd. (CN) 2016-05-11 CN disclosed
CN-102757463-A Method for preparing aryl dialkyl phosphate from aryl sulfonate UNIV SHANGHAI JIAOTONG 2012-10-31 CN disclosed
US-5488172-A Chiral phosphorus compounds HOFFMANN-LA ROCHE INC. (US) 1996-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11325929-B2 Phosphorus-containing compound and preparation and use thereof INPP5D, CXCL12, INPPL1 HCRTR1 3611/4885MEN1 3056/4885POLB 2721/4885
US-20200131206-A1 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF INPP5D, CXCL12, INPPL1 HCRTR1 3611/4885MEN1 3056/4885POLB 2721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.