SCHEMBL8994736

SCHEMBL8994736

CC(=O)OC1CC[C@H]2C(C)(C)CCC[C@]2(C)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
ACHE P22303 1/20 0.34
PLA2G2A P14555 2/20 0.34
TDP1 Q9NUW8 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TRPM2 O94759 1/20 0.33
ALOX15 P16050 1/20 0.33
PLA2G1B P04054 2/20 0.32
NR1H4 Q96RI1 2/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
EPAS1 Q99814 1/20 0.32
TP53 P04637 2/20 0.32
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1427712 1.00 CYP3A4 (0.40) CYP3A4ACHEPLA2G2ATDP1CYP2C9
SCHEMBL26250381 1.00 CYP3A4 (0.40) CYP3A4ACHEPLA2G2ATDP1CYP2C9
SCHEMBL30879479 1.00 CYP3A4 (0.40) CYP3A4ACHEPLA2G2ATDP1CYP2C9
SCHEMBL3262814 1.00 CYP3A4 (0.40) CYP3A4ACHEPLA2G2ATDP1CYP2C9
SCHEMBL7039925 0.78 CYP3A4 (0.40) CYP3A4ACHEPLA2G2ATDP1CYP2C9
SCHEMBL31410915 0.76 IDO1 (0.32) PTPN1
SCHEMBL22702733 0.76 PTPN1 (0.32) PTPN1
SCHEMBL9418513 0.74 CYP3A4 (0.33) CYP3A4TDP1CYP2C9CYP2C19TP53
SCHEMBL15874145 0.72 APLNR (0.39) TDP1CYP2C19ALOX15PTPN2PTPN1
SCHEMBL11797090 0.71 PTPN1 (0.35) CYP3A4PTPN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023156429-A1 PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES FIRMENICH SA (CH) 2023-08-24 WO disclosed
US-5552379-A FLORAL, FOR COSMETICS AND HOUSEHOLD ITEMS FIRMENICH SA (CH) 1996-09-03 US disclosed
US-5527769-A AROMATIC ALDEHYDES OR ACETALS IMPART FLORAL FRAGRANCES FIRMENICH SA (CH) 1996-06-18 US disclosed