Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994708 | 0.87 | KMT2A (0.49) | HPGDKMT2AMEN1TSHRPOLB | |
| SCHEMBL7212940 | 0.84 | HPGD (0.41) | HPGDKMT2AMEN1RAB9ATNKS | |
| SCHEMBL25798784 | 0.81 | KMT2A (0.53) | HPGDKMT2AMEN1RAB9ALMNA | |
| SCHEMBL23658969 | 0.81 | KMT2A (0.53) | HPGDKMT2AMEN1RAB9ALMNA | |
| SCHEMBL25798781 | 0.81 | KMT2A (0.53) | HPGDKMT2AMEN1RAB9ALMNA | |
| SCHEMBL29516997 | 0.78 | TNKS (0.43) | HPGDKMT2AMEN1RAB9ATNKS | |
| SCHEMBL21327676 | 0.73 | HPGD (0.52) | HPGDKMT2AMEN1LMNATSHR | |
| SCHEMBL9441174 | 0.73 | MEN1 (0.47) | KMT2AMEN1TSHRPOLBALDH1A1 | |
| SCHEMBL9441197 | 0.71 | MAPT (0.43) | KMT2AMEN1RAB9ATNKSTNKS2 | |
| SCHEMBL25798804 | 0.71 | KMT2A (0.51) | HPGDKMT2AMEN1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488172-A | Chiral phosphorus compounds | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |