Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994755 | 0.87 | HPGD (0.39) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL14259711 | 0.84 | KMT2A (0.60) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL5715738 | 0.83 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL5829821 | 0.82 | ALDH1A1 (0.43) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL8994715 | 0.81 | KMT2A (0.49) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL18486442 | 0.80 | KMT2A (0.60) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL29559391 | 0.78 | KMT2A (0.54) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL6130232 | 0.78 | HTT (0.46) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL8908268 | 0.78 | L3MBTL1 (0.44) | KMT2AMEN1HTTPOLBL3MBTL1 | |
| SCHEMBL5572022 | 0.78 | KMT2A (0.50) | KMT2AMEN1HTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488172-A | Chiral phosphorus compounds | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |