Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995028 | 1.00 | LTB4R (0.45) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL8994922 | 0.92 | LTB4R (0.46) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL8994916 | 0.92 | LTB4R (0.46) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL8995040 | 0.92 | LTB4R (0.46) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL8995075 | 0.88 | LTB4R (0.48) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL8747961 | 0.86 | GAA (0.53) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL7717126 | 0.86 | GAA (0.53) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL8994847 | 0.82 | LTB4R (0.46) | LTB4RGAARAB9ANPC1LMNA | |
| SCHEMBL7711184 | 0.82 | LTB4R (0.64) | LTB4RRAB9ANPC1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL8995077 | 0.81 | LTB4R (0.63) | LTB4RRAB9ANPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5451700-A | Leukotriene inhibitors | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |