⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898931 | 0.79 | — | — | |
| SCHEMBL3361574 | 0.79 | — | — | |
| SCHEMBL29429113 | 0.79 | — | — | |
| SCHEMBL29479581 | 0.79 | — | — | |
| SCHEMBL27759683 | 0.77 | — | — | |
| SCHEMBL362876 | 0.75 | — | — | |
| SCHEMBL115716 | 0.75 | — | — | |
| SCHEMBL2487120 | 0.75 | — | — | |
| SCHEMBL440236 | 0.75 | — | — | |
| SCHEMBL933261 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712969-A1 | CYCLIN INHIBITORS | Circle Pharma, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20240408169-A1 | CYCLIN INHIBITORS | CIRCLE PHARMA, INC. | 2024-12-12 | — | — | US | disclosed |
| EP-4472968-A1 | INHIBITORS OF RAF KINASES | PIERRE FABRE MEDICAMENT (FR) | 2024-12-11 | — | — | EP | disclosed |
| CN-118974036-A | Inhibitors of RAF kinase | 皮埃尔法布雷医药公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118271285-A | Azetidine-containing amide derivative, preparation method and application thereof | 贵州大学 | 2024-07-02 | — | — | CN | disclosed |
| US-20240182467-A1 | INHIBITORS OF RAF KINASES | Pierre Fabre Médicament (FR) | 2024-06-06 | — | — | US | disclosed |
| US-11814384-B2 | Inhibtors of Raf kinases | KINNATE BIOPHARMA INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230303566-A1 | INHIBITORS OF RAF KINASES | Pierre Fabre Médicament (FR) | 2023-09-28 | — | — | US | disclosed |
| WO-2023150681-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| US-10933056-B2 | 3-(1H-pyrazol-4-yl)pyridine allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2021-03-02 | — | — | US | disclosed |
| WO-2007002254-A2 | BENZOCYCLOHEPTAPYRIDINES AS INHIBITORS OF THE RECEPTOR TYROSINE KINASE MET | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060293358-A1 | Tyrosine kinase inhibitors | MERCK SHARP & DOHME LLC | 2006-12-28 | — | — | US | disclosed |
| EP-1572655-A2 | NOVEL ARYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| US-20040242871-A1 | Novel arylheteroalkylamine derivatives | ASTRAZENECA AB (SE) | 2004-12-02 | — | — | US | disclosed |
| WO-2002090332-A2 | NOVEL AEYLHETEROALKYLAMINΕ DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-14 | — | — | WO | disclosed |
| EP-0634413-A1 | Herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | disclosed |
| US-5336771-A | Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines | PFIZER INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0445950-B1 | Novel pyridine derivatives and processes for their synthesis | PFIZER (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5068333-A | 6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R configuration | PFIZER INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0445950-A1 | Novel pyridine derivatives and processes for their synthesis | PFIZER INC. (US) | 1991-09-11 | — | — | EP | disclosed |