SCHEMBL362876

SCHEMBL362876

Nc1ncc(Cl)cc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792863 1.00
SCHEMBL29479581 0.80
SCHEMBL3361574 0.80
SCHEMBL305370 0.76
SCHEMBL30700775 0.76
SCHEMBL1346652 0.76 MAP4K4 (0.58)
SCHEMBL913127 0.75
SCHEMBL120637 0.75
SCHEMBL362099 0.75
SCHEMBL971307 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111349043-B Intermediate for preparing pimenib and preparation method and application thereof 上海医药工业研究院 2022-09-27 CN claimed
CN-111349043-A Intermediate for preparing pimenib and preparation method and application thereof 上海医药工业研究院 2020-06-30 CN claimed
CN-104744463-A Method for synthesizing 6-chloro-8-bromoimidazo[1,2-a]pyridine SHANDONG YOUBANG BIOCHEMICAL TECHNOLOGY CO LTD 2015-07-01 CN claimed
CN-100418966-C 8-iodo-imidazo[1,2-alpha] pyridine-3-acetamide compound and preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-09-17 CN claimed
CN-1858050-A 8-iodo-imidazo[1,2-alpha] pyridine-3-acetamide compound and preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-11-08 CN claimed
EP-4213843-B1 MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2026-05-06 EP disclosed
US-12590102-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2026-03-31 US disclosed
US-12583870-B2 Azaheteroaryl compound and application thereof SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2026-03-24 US disclosed
US-12559491-B2 Modified imidazopyridines as glucosylceramide synthase inhibitors MERCK SHARP & DOHME LLC (US) 2026-02-24 US disclosed
US-20250340778-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND APPARATUS INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2025-11-06 US disclosed
US-20250333647-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND APPARATUS INCLUDING ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2025-10-30 US disclosed
US-12441724-B2 Inhibitors of plasma kallikrein and uses thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-10-14 US disclosed
US-5861419-A ANTIINFLAMMATORY AGENTS; ANTIPYRETICS, ANALGESICS; ETORICOXIB PATENT MERCK FROSST CANAD, INC. (CA) 1999-01-19 US disclosed
WO-1998003484-A1 SUBSTITUTED PYRIDINES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS MERCK FROSST CANADA INC. (CA) 1998-01-29 WO disclosed
US-5336771-A Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines PFIZER INC. (US) 1994-08-09 US disclosed
EP-0445950-B1 Novel pyridine derivatives and processes for their synthesis PFIZER (US) 1994-06-08 EP disclosed
US-5068333-A 6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R configuration PFIZER INC. (US) 1991-11-26 US disclosed
EP-0445950-A1 Novel pyridine derivatives and processes for their synthesis PFIZER INC. (US) 1991-09-11 EP disclosed
US-4847263-A SEDATIVES, ANXIOLITIC AGENTS SYNTHELABO (FR) 1989-07-11 US disclosed
US-4033975-A Process for the production of 2-amino-3-hydroxypyridine derivatives CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed