SCHEMBL8995089

SCHEMBL8995089

NC(=O)C(O)Cc1ccccc1.O=C(O)C(O)Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55
EPHX1 P07099 1/20 0.55
CYP1A2 P05177 1/20 0.53
SRR Q9GZT4 2/20 0.50
SLC1A3 P43003 2/20 0.50
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
KDM6B O15054 1/20 0.49
PTPRA P18433 1/20 0.47
CPA3 P15088 3/20 0.47
CPA1 P15085 2/20 0.47
FOLH1 Q04609 1/20 0.47
CPB1 P15086 1/20 0.47
CPB2 Q96IY4 1/20 0.47
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3432001 0.94 EPHX1 (0.60) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7474169 0.94 EPHX1 (0.60) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL414455 0.94 EPHX1 (0.60) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL57558 0.90 CYP1A2 (0.64) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8953468 0.90 CYP1A2 (0.64) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL197252 0.90 CYP1A2 (0.64) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL180366 0.90 CYP1A2 (0.64) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL1374832 0.88 CYP1A2 (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5800210 0.88 CYP1A2 (0.61) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL1374834 0.88 CYP1A2 (0.61) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508181-A REACTING AN ALPHA-HYDROXYNITRILE (OR MIXTURE WITH AN ALDEHYDE) WITH HYDROGEN CYANIDE IN PRESENCE OF PHOSPHITE OR HYPOPHOSPHITE IONS NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1996-04-16 US disclosed