Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.60 |
| ▸ | EBP | Q15125 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706125 | 0.87 | EBP (0.72) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL5215578 | 0.82 | KDM4E (0.58) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL492266 | 0.82 | MCHR1 (0.60) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL2319666 | 0.82 | MCHR1 (0.60) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL2958271 | 0.81 | HRH3 (0.59) | CYP1A2LTA4HCYP2C19HRH3 | |
| SCHEMBL5856160 | 0.81 | MCHR1 (0.59) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL6181597 | 0.80 | EBP (0.53) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL3420518 | 0.79 | EBP (0.64) | MCHR1EBPSIGMAR1CYP1A2LTA4H | |
| SCHEMBL2560917 | 0.79 | THRA (0.54) | HRH3 | |
| SCHEMBL10970158 | 0.79 | MCHR1 (0.91) | MCHR1EBPSIGMAR1CYP1A2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |