Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237871 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL13246765 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL10711163 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL29242363 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL29242313 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL257751 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL6469949 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL10941945 | 0.76 | MAPT (0.53) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL29242353 | 0.76 | MAPT (0.52) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 | |
| SCHEMBL11826859 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTRAB9ACTDSP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |