Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429081 | 0.98 | IDO1 (0.44) | IDO1CHRM3TDP1L3MBTL1APP | |
| SCHEMBL9347610 | 0.88 | IDO1 (0.52) | IDO1CHRM3TDP1L3MBTL1APP | |
| SCHEMBL4222448 | 0.86 | IDO1 (0.50) | IDO1CHRM3APPRXRARXRB | |
| SCHEMBL25215440 | 0.84 | IDO1 (0.48) | IDO1CHRM3APPRXRARXRB | |
| SCHEMBL11314244 | 0.83 | LTA4H (0.41) | IDO1CHRM3TDP1L3MBTL1PTPN2 | |
| SCHEMBL134086 | 0.83 | IDO1 (0.61) | IDO1CHRM3APPRXRARXRB | |
| SCHEMBL20317448 | 0.81 | MEN1 (0.45) | TDP1L3MBTL1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL21578433 | 0.81 | IDO1 (0.58) | IDO1CHRM3APPRXRARXRB | |
| SCHEMBL9342149 | 0.81 | IDO1 (0.58) | IDO1CHRM3APPRXRARXRB | |
| SCHEMBL9342899 | 0.81 | IDO1 (0.58) | IDO1CHRM3APPRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8225733-A | — | — | None | — | — | JP | disclosed |
| JP-H08225733-A | GAMMA-RAY-RESISTANT POLYCARBONATE RESIN COMPOSITION | TEIJIN LTD | 1996-09-03 | — | — | JP | disclosed |
| EP-0664316-A1 | Polycarbonate composition having improved resistance to gamma-ray radiation | TEIJIN LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |