Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831765 | 0.98 | NFKB1 (0.42) | NFKB1NFKB2RELAMGLLFAAH | |
| Methylamine SCHEMBL27504132 | 0.88 | NFKB1 (0.34) | NFKB1NFKB2RELAMGLLFAAH | |
| Ethylamine SCHEMBL27838288 | 0.86 | NFKB1 (0.33) | NFKB1NFKB2RELAMGLLFAAH | |
| SCHEMBL9080971 | 0.74 | — | — | |
| SCHEMBL27571420 | 0.73 | NFKB1 (0.38) | NFKB1NFKB2RELAMGLLFAAH | |
| SCHEMBL10637390 | 0.71 | NFKB1 (0.37) | NFKB1NFKB2RELAMGLLFAAH | |
| SCHEMBL3679463 | 0.66 | TRPV1 (0.73) | FAAHTRPV1TSHRPPARGFFAR1 | |
| SCHEMBL30105511 | 0.66 | TRPV1 (0.73) | FAAHTRPV1TSHRPPARGFFAR1 | |
| SCHEMBL3682342 | 0.66 | TRPV1 (0.73) | FAAHTRPV1TSHRPPARGFFAR1 | |
| SCHEMBL3682356 | 0.66 | TRPV1 (0.73) | FAAHTRPV1TSHRPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190687-B | Configuration-limited carbon-bridged single metallocene compound and preparation and application thereof | PETROCHINA CO LTD | 2014-11-19 | — | — | CN | disclosed |
| CN-102190749-B | Ethylene/alpha-olefin copolymerization method | PETROCHINA CO LTD | 2013-02-20 | — | — | CN | disclosed |
| CN-101434668-B | Polyolefins | MITSUI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-02-22 | — | — | CN | disclosed |
| CN-102190749-A | Ethylene/alpha-olefin copolymerization method | PETROCHINA CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-102190687-A | Configuration-limited carbon-bridged single metallocene compound and preparation and application thereof | PETROCHINA CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-101434668-A | Polyolefins | MITSUI CHEMICALS INC (JP) | 2009-05-20 | — | — | CN | disclosed |
| CN-100434433-C | Metallocene compound and preparation method thereof, olefin polymerization catalyst, polyolefin and preparation method thereof | MITSUI CHEMICALS INC (JP) | 2008-11-19 | — | — | CN | disclosed |
| CN-1228288-C | Catalyst system for trimerisation of olefins | STICHTING DUTCH POLYMER INST (NL) | 2005-11-23 | — | — | CN | disclosed |
| CN-1492847-A | Catalyst system for trimerisation of olefins | ˹�ٴĶ������ۺ���ѧ�� | 2004-04-28 | — | — | CN | disclosed |
| CN-1327448-A | Metallocene compound and preparation method thereof, olefin polymerization catalyst, polyolefin and preparation method thereof | MITSUI CHEMICALS INC (JP) | 2001-12-19 | — | — | CN | disclosed |
| US-5565534-A | POLYMERIZING OLEFIN IN PRESENCE OF STEREORIGID METALLOCENE | HOECHST AG (DE) | 1996-10-15 | — | — | US | disclosed |