Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343777 | 1.00 | NOS2 (0.46) | NOS2KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL2614966 | 0.83 | KDM4E (0.46) | NOS2KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL1838370 | 0.80 | NOS2 (0.42) | NOS2CCR1 | |
| SCHEMBL30819694 | 0.80 | NOS2 (0.42) | NOS2CCR1 | |
| SCHEMBL28648289 | 0.80 | NOS2 (0.42) | NOS2CCR1 | |
| SCHEMBL20897039 | 0.80 | TAAR1 (0.47) | NOS2CCR1CCR8NOS3PDE8B | |
| SCHEMBL13040616 | 0.78 | NOS2 (0.58) | NOS2NOS3 | |
| SCHEMBL1833445 | 0.78 | NOS2 (0.41) | NOS2KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL1845293 | 0.78 | NOS2 (0.44) | NOS2MAOA | |
| SCHEMBL1249740 | 0.78 | NOS2 (0.41) | NOS2KDM4EUSP2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518860-A | IMPROVED ADHESION TO SILICON OXIDE AND NITRIDE SUBSTRATES | TOKYO OHKA KOGYO CO., LTD. (JP) | 1996-05-21 | — | — | US | claimed |
| US-4457934-A | ESTER DERIVATIVE OF PYRIDINE | STAUFFER CHEMICAL COMPANY (US) | 1984-07-03 | — | — | US | disclosed |