Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399245 | 1.00 | KMT2A (0.51) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL8995899 | 1.00 | KMT2A (0.51) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL1405475 | 0.86 | CA1 (0.60) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL1405477 | 0.86 | CA1 (0.60) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL14253085 | 0.80 | KMT2A (0.53) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL18065723 | 0.78 | ALDH1A1 (0.52) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1405268 | 0.77 | KMT2A (0.58) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL31071661 | 0.77 | KMT2A (0.58) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL1405267 | 0.77 | KMT2A (0.58) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL55260 | 0.77 | CA1 (0.60) | KMT2AMEN1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527704-B1 | Dyestuffs, process for their preparation and the use thereof | CIBA GEIGY AG (CH) | 1996-08-28 | — | — | EP | disclosed |
| US-5234467-A | Disazo and monoazo dye mixtures; colorfastness; good affinity in short liquors; water solubility | CIBA-GEIGY CORPORATION (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0527704-A2 | Dyestuffs, process for their preparation and the use thereof | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | disclosed |
| EP-0062200-B1 | DISAZO DYESTUFFS | BASF Aktiengesellschaft (DE) | 1985-01-23 | — | — | EP | disclosed |