Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.71 |
| ▸ | APP | P05067 | 4/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947483 | 0.90 | MAOB (0.61) | MAOBAPPESR1ESR2EGFR | |
| SCHEMBL11850978 | 0.89 | MAOB (0.80) | MAOBAPPESR1ESR2MAOA | |
| SCHEMBL28751161 | 0.86 | MAOB (0.53) | MAOBAPPEGFRSRCKDM4E | |
| SCHEMBL7818265 | 0.85 | APP (0.74) | MAOBAPPESR1ESR2EGFR | |
| SCHEMBL735803 | 0.83 | MAOB (0.71) | MAOBAPPESR1ESR2MAOA | |
| SCHEMBL9947476 | 0.83 | MAOB (0.71) | MAOBAPPESR1ESR2MAOA | |
| SCHEMBL3983367 | 0.82 | MAOB (1.00) | MAOBESR1ESR2MAOAADORA3 | |
| SCHEMBL7117044 | 0.81 | MAOB (0.69) | MAOBAPPESR1ESR2MAOA | |
| SCHEMBL14900924 | 0.81 | APP (0.68) | MAOBAPPESR1ESR2EGFR | |
| SCHEMBL14231743 | 0.81 | MAOB (0.71) | MAOBMAOAADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1410422-A | Benzfuran compound | SHARP KK (JP) | 2003-04-16 | — | — | CN | disclosed |
| EP-0527704-B1 | Dyestuffs, process for their preparation and the use thereof | CIBA GEIGY AG (CH) | 1996-08-28 | — | — | EP | disclosed |
| US-5302704-A | For dyeing polyamide fibers; colorfastness | CIBA-GEIGY CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0527704-A2 | Dyestuffs, process for their preparation and the use thereof | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | disclosed |