SCHEMBL3983367

SCHEMBL3983367

Cc1ccc2oc(-c3ccccc3)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 1.00
KDM4E B2RXH2 3/20 0.61
HPGD P15428 3/20 0.61
MAOA P21397 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TP53 P04637 2/20 0.61
CYP3A4 P08684 2/20 0.61
MAPT P10636 2/20 0.61
HSD17B10 Q99714 2/20 0.61
NPC1 O15118 1/20 0.51
POLB P06746 1/20 0.51
CASP3 P42574 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
FFAR1 O14842 1/20 0.51
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11850978 0.89 MAOB (0.80) MAOBMAOAESR1ESR2ADORA3
SCHEMBL11699010 0.88 MAOB (0.78) MAOBKDM4EHPGDMAOAALDH1A1
SCHEMBL8993319 0.87 MAOB (0.77) MAOBKDM4EHPGDMAOAALDH1A1
SCHEMBL21860421 0.86 MAOB (0.74) MAOBKDM4EHPGDMAOAALDH1A1
SCHEMBL11713027 0.85 MAOB (0.74) MAOBKDM4EHPGDMAOAALDH1A1
SCHEMBL14231743 0.84 MAOB (0.71) MAOBMAOAALDH1A1ADORA3
SCHEMBL11711558 0.82 MAOB (0.70) MAOBKDM4EHPGDMAOAALDH1A1
SCHEMBL10901534 0.82 MAOB (0.70) MAOBKDM4EHPGDMAOAALDH1A1
SCHEMBL9947476 0.82 MAOB (0.71) MAOBMAOAESR1ESR2ADORA3
SCHEMBL735803 0.82 MAOB (0.71) MAOBMAOAESR1ESR2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
US-20210384446-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2021-12-09 US disclosed
US-11133478-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-09-28 US disclosed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 US disclosed
US-20190221753-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 US disclosed
US-10297765-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-05-21 US disclosed
CN-108033935-A A kind of preparation method of polysubstituted benzofuran derivative 上海应用技术大学 2018-05-15 CN disclosed
CN-105732552-B The preparation method of 2 or 3 thio benzofuran compounds 天津师范大学 2017-12-01 CN disclosed
US-20170073359-A1 Optically-Detectable Enzyme Substrates and Their Method of Use MOLECULAR PROBES, INC. 2017-03-16 US disclosed
US-8318450-B2 Optically-detectable enzyme substrates and their method of use Life Technologies Corporation (US) 2012-11-27 US disclosed
US-20120040380-A1 OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20100314615-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-12-16 US disclosed
US-20100314615-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-12-16 US disclosed
EP-2239259-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-10-13 EP disclosed
US-20090047692-A1 OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE INVITROGEN CORPORATION (US) 2009-02-19 US disclosed
US-7473786-B1 Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts UNIVERSITY OF MASSACHUSETTS (US) 2009-01-06 US disclosed
US-7473786-B1 Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts UNIVERSITY OF MASSACHUSETTS (US) 2009-01-06 US disclosed
US-7473786-B1 Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts UNIVERSITY OF MASSACHUSETTS (US) 2009-01-06 US disclosed
US-4009184-A Amino carbonyl derivatives of benzofurans, processes for their production, and pharmaceutical compositions containing the same 2-phenyl-3-[3-dialkylaminopropanoyl]benzofuran compounds KALI-CHEMIE AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100314615-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC MAOB 39/4885KDM4E 366/4885HPGD 2757/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 MAOB 2764/4885KDM4E 2392/4885HPGD 1539/4885
US-20170073359-A1 Optically-Detectable Enzyme Substrates and Their Method of Use MGAM, LCT, GAA MAOB 203/4885KDM4E 3086/4885HPGD 650/4885
US-20210384446-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC MAOB 39/4885KDM4E 366/4885HPGD 2757/4885
US-11133478-B2 Aromatic amine derivative and organic electroluminescent device using the same DDT, TYR, DDC MAOB 39/4885KDM4E 366/4885HPGD 2757/4885
US-10297765-B2 Aromatic amine derivative and organic electroluminescent device using the same DDT, TYR, DDC MAOB 39/4885KDM4E 366/4885HPGD 2757/4885
US-20090047692-A1 OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE MGAM, LCT, GAA MAOB 203/4885KDM4E 3086/4885HPGD 650/4885
US-20190221753-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DDT, TYR, DDC MAOB 39/4885KDM4E 366/4885HPGD 2757/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 MAOB 2940/4885KDM4E 1702/4885HPGD 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.