SCHEMBL8995968

SCHEMBL8995968

COC(C)Nc1ccc(N)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
RECQL P46063 2/20 0.46
THRB P10828 1/20 0.46
ALOX15 P16050 1/20 0.46
HIF1A Q16665 1/20 0.46
TSHR P16473 3/20 0.41
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
S100B P04271 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SKP2 Q13309 1/20 0.33
EIF2AK4 Q9P2K8 1/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPK1 P28482 1/20 0.31
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172486 0.88 ALDH1A1 (0.42) ALDH1A1CYP3A4TDP1RECQLTHRB
SCHEMBL8681664 0.81 ALDH1A1 (0.42) ALDH1A1CYP3A4TDP1RECQLTHRB
SCHEMBL8190222 0.79 CYP3A4 (0.50) ALDH1A1CYP3A4TDP1RECQLTHRB
SCHEMBL8634761 0.79 ALDH1A1 (0.36) ALDH1A1RECQLTSHRKDM4ELMNA
SCHEMBL11231333 0.79 KDM4E (0.30) ALDH1A1TDP1GAAMEN1KMT2A
SCHEMBL9695004 0.79 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1RECQLTHRB
SCHEMBL14028547 0.78 ALDH1A1 (0.42) ALDH1A1CYP3A4TDP1RECQLTHRB
SCHEMBL7774940 0.78 CYP3A4 (0.53) ALDH1A1CYP3A4TDP1RECQLTHRB
SCHEMBL8665713 0.77 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1THRBTSHR
SCHEMBL11669125 0.77 SKP2 (0.43) ALDH1A1CYP3A4TDP1RECQLTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595102-B1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-08-07 EP disclosed
EP-0671656-A2 Silver halide light-sensitive color photographic material and method of preparing color proof KONICA CORPORATION (JP) 1995-09-13 EP disclosed
EP-0595102-A1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-04 EP disclosed
US-5194348-A Nonfading, deactivation of amine developers, stabilizers FUJI PHOTO FILM CO., LTD. (JP) 1993-03-16 US disclosed
US-5128237-A Incorporating a coupler residue capale of releasing a timing group also capable of releasing a scavenger for the oxidation product of the developer; color reproduction; sharpness KONICA CORPORATION (JP) 1992-07-07 US disclosed
EP-0083377-B2 SILVER HALIDE COLOR PHOTOGRAPHIC SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-06-17 EP disclosed
EP-0258662-B1 COLOR PHOTOGRAPHS AND METHOD FOR PREPARATION OF THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1992-05-27 EP disclosed
US-4895793-A 1,1'SPIROBISINDANE COMPOUNDS AS DYE STABILIZERS; ANTISOILANTS FUJI PHOTO FILM CO., LTD. (JP) 1990-01-23 US disclosed
US-4894318-A Storage stability FUJI PHOTO FILM CO., LTD. (JP) 1990-01-16 US disclosed
EP-0258662-A2 Color photographs and method for preparation of the same FUJI PHOTO FILM CO., LTD. (JP) 1988-03-09 EP disclosed
US-4596764-A Processing by color development process including subjecting material to amino-containing mercapto compound FUJI PHOTO FILM CO., LTD. (JP) 1986-06-24 US disclosed
US-4511648-A Light-sensitive silver halide color photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-04-16 US disclosed
US-4446226-A SIVER IODOBROMIDE, SILVER IODIDE, CRYSTAL STRUCTURE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-05-01 US disclosed
EP-0083377-A1 SILVER HALIDE COLOR PHOTOGRAPHIC SENSITIVE MATERIAL KONICA CORPORATION (JP) 1983-07-13 EP disclosed
EP-0070183-A1 Light-sensitive color photographic material KONICA CORPORATION (JP) 1983-01-19 EP disclosed
US-4192680-A SPECIFIED CONCENTRATION RANGE OF BROMIDE ION IN PRESENCE OF CERTAIN TYPE OF YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-11 US disclosed
US-4021248-A SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed