Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996019 | 0.90 | FTO (0.76) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8995993 | 0.90 | FTO (0.76) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8996090 | 0.88 | FTO (0.73) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8996010 | 0.88 | FTO (0.73) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8995992 | 0.88 | FTO (0.61) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL9065481 | 0.87 | FTO (0.69) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8996241 | 0.85 | FTO (0.58) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8996027 | 0.85 | FTO (1.00) | FTOPKMEGFRMAPTMAPK1 | |
| SCHEMBL8996037 | 0.85 | EGFR (0.76) | FTOPKMTP53SMN1; SMN2THRB | |
| SCHEMBL8996006 | 0.84 | FTO (0.59) | FTOPKMTP53SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |