Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094701 | 0.85 | NPSR1 (0.48) | KMT2AMEN1PTGIRPTGDRNPSR1 | |
| SCHEMBL2094699 | 0.84 | PTGIR (0.47) | KMT2AMEN1PTGIRPTGDRNPSR1 | |
| SCHEMBL1118562 | 0.84 | PTGIR (0.47) | KMT2AMEN1PTGIRPTGDRNPSR1 | |
| SCHEMBL197621 | 0.83 | NPSR1 (0.56) | KMT2AMEN1TSHRPTGIRPTGDR | |
| SCHEMBL741752 | 0.82 | NPSR1 (0.64) | KMT2AMEN1TSHRNPSR1NPC1 | |
| Hydrochloric Acid SCHEMBL27946912 | 0.81 | HTR3E (0.47) | KMT2AMEN1PTGIRPTGDRNPSR1 | |
| Hydrochloric Acid SCHEMBL8550497 | 0.80 | NPSR1 (0.61) | KMT2AMEN1TSHRNPSR1NPC1 | |
| SCHEMBL8044893 | 0.80 | NPSR1 (0.61) | KMT2AMEN1TSHRNPSR1NPC1 | |
| SCHEMBL27667245 | 0.80 | KMT2A (0.49) | KMT2AMEN1TSHRNPSR1NPC1 | |
| SCHEMBL4613837 | 0.80 | MAPT (0.44) | KMT2ANPSR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |