SCHEMBL8996218

SCHEMBL8996218

Oc1ccc2c3cccc4cccc(c5cccc1c52)c43

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.58
HPGD P15428 3/20 0.58
THRB P10828 2/20 0.58
MAPT P10636 2/20 0.58
TSHR P16473 2/20 0.58
APP P05067 1/20 0.58
ALOX15 P16050 1/20 0.58
CASP1 P29466 1/20 0.58
SNCA P37840 1/20 0.58
RECQL P46063 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CYP1A2 P05177 5/20 0.52
ALDH1A1 P00352 3/20 0.48
IDO1 P14902 1/20 0.48
ERBB2 P04626 1/20 0.43
FYN P06241 1/20 0.43
MAOA P21397 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
PTPN22 Q9Y2R2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28335016 0.98 HSD17B10 (0.56) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL15892260 0.90 RECQL (0.70) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL10884065 0.90 RECQL (0.70) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL30849902 0.85 CYP1A2 (0.67) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL9967825 0.84 CYP1A2 (0.44) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL29362339 0.83 HPGD (0.55) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL29571791 0.83 HPGD (0.55) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL218996 0.83 HPGD (0.55) HSD17B10HPGDTHRBMAPTTSHR
SCHEMBL14856896 0.81 HSD17B10 (0.48) HSD17B10HPGDTHRBMAPTTSHR
1-Naphthol SCHEMBL2393593 0.81 CYP1A2 (0.81) HSD17B10HPGDTHRBMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502325-A Processing additives and uses of same in rotational molding CYTEC TECH CORP 2014-01-08 CN claimed
US-5563151-A PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-10-08 US claimed
EP-0623116-A1 AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-11-09 EP claimed
WO-1993014072-A1 AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-07-22 WO claimed
CN-113661445-B High-thickness spin-on carbon hard mask composition and patterning method using the same 荣昌化学制品株式会社 2024-12-10 CN disclosed
US-12105421-B2 Highly thick spin-on-carbon hard mask composition and patterning method using same YOUNG CHANG CHEMICAL CO., LTD (KR) 2024-10-01 US disclosed
WO-2023189803-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
WO-2023189799-A1 SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
US-20230221643-A1 HARD MASK-FORMING COMPOSITION AND METHOD FOR MANUFACTURING ELECTRONIC COMPONENT TOKYO OHKA KOGYO CO LTD (JP) 2023-07-13 US disclosed
US-11650503-B2 Hard mask-forming composition and method for manufacturing electronic component TOKYO OHKA KOGYO CO., LTD. (JP) 2023-05-16 US disclosed
CN-109844639-B Spin-on carbon hard mask composition with high etching resistance and patterning method using the same 荣昌化学制品株式会社 2022-09-02 CN disclosed
US-20220179318-A1 HIGHLY THICK SPIN-ON-CARBON HARD MASK COMPOSITION AND PATTERNING METHOD USING SAME YOUNG CHANG CHEMICAL CO., LTD (KR) 2022-06-09 US disclosed
US-20190258163-A1 HIGH ETCH RESISTANCE SPIN-ON CARBON HARD MASK COMPOSITION AND PATTERNING METHOD USING SAME YCCHEM CO., LTD. (KR) 2019-08-22 US disclosed
CN-109844639-A The spin-coating carbon hardmask composition of high elching resistant and the patterning method using the composition 荣昌化学制品株式会社 2019-06-04 CN disclosed
US-20190044081-A1 ORGANIC LIGHT-EMITTING COMPONENT AND METHOD FOR PRODUCING AN ORGANIC LIGHT-EMITTING COMPONENT DOLYA HOLDCO 5 LIMITED (IE) 2019-02-07 US disclosed
EP-2492988-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sumitomo Chemical Company, Limited (JP) 2012-08-29 EP disclosed
US-20120199825-A1 ORGANIC ELECTROLUMINESCENT DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-09 US disclosed
US-5563151-A PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-10-08 US disclosed
EP-0623116-A1 AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-11-09 EP disclosed
WO-1993014072-A1 AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-07-22 WO disclosed