1-Naphthol

1-Naphthol

SCHEMBL2393593

Oc1cccc2ccccc12.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.81
HSD17B10 Q99714 4/20 0.54
ALDH1A1 P00352 3/20 0.54
THRB P10828 2/20 0.54
HPGD P15428 2/20 0.54
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPT P10636 2/20 0.52
APP P05067 1/20 0.52
ALOX15 P16050 1/20 0.52
CASP1 P29466 1/20 0.52
SNCA P37840 1/20 0.52
RECQL P46063 1/20 0.52
PTPN22 Q9Y2R2 1/20 0.48
IDO1 P14902 1/20 0.48
KDM4E B2RXH2 2/20 0.47
PLAU P00749 1/20 0.47
MAPKAPK2 P49137 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
NQO2 P16083 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL28791415 0.91 CYP1A2 (0.81) CYP1A2HSD17B10ALDH1A1THRBHPGD
Catechol SCHEMBL29115865 0.90 CYP1A2 (0.64) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL29767730 0.90 CYP1A2 (1.00) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL3416 0.90 CYP1A2 (1.00) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL273260 0.90 CYP1A2 (1.00) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL10486461 0.90 CYP1A2 (1.00) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL3924043 0.87 CYP1A2 (0.94) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL4196679 0.87 CYP1A2 (0.94) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL21490911 0.87 CYP1A2 (0.94) CYP1A2HSD17B10ALDH1A1THRBHPGD
1-Naphthol SCHEMBL11247168 0.87 CYP1A2 (0.94) CYP1A2HSD17B10ALDH1A1THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9085491-B2 Carbon-coated lithium titanium spinel SUED-CHEMIE IP GMBH & CO. KG (DE) 2015-07-21 US disclosed
US-20140175687-A1 CARBON-COATED LITHIUM TITANIUM SPINEL Sued-Chemie IP GmbH & Co., KG (DE) 2014-06-26 US disclosed
US-20110217593-A1 CARBON-COATED LITHIUM TITANIUM SPINEL SUD-CHEMIE AG (DE) 2011-09-08 US disclosed