Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | FGB | P02675 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996345 | 0.89 | EGFR (0.56) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8996393 | 0.86 | MAPT (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3277257 | 0.80 | KMT2A (0.61) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8996376 | 0.80 | TTR (0.51) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8996244 | 0.78 | MAPT (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12581978 | 0.77 | MAPT (0.53) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23198954 | 0.75 | NPC1 (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10930907 | 0.75 | TOP1 (0.49) | MAPTALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL9522230 | 0.75 | MAPT (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27401718 | 0.74 | EGFR (0.55) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | claimed |
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |