Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996410 | 0.89 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8996393 | 0.87 | MAPT (0.50) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL27401718 | 0.86 | EGFR (0.55) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL27404462 | 0.82 | EGFR (0.50) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL8996409 | 0.80 | KDM4E (0.64) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL10974170 | 0.78 | EGFR (0.74) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL8996312 | 0.77 | TTR (0.71) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL3417492 | 0.76 | EGFR (0.76) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL11432460 | 0.75 | EGFR (0.45) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL8947495 | 0.74 | EGFR (0.73) | EGFRPIM1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |