Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.73 |
| ▸ | AURKA | O14965 | 2/20 | 0.73 |
| ▸ | CDC25B | P30305 | 2/20 | 0.73 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.73 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.73 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.73 |
| ▸ | PIM1 | P11309 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27378113 | 0.98 | TXNRD1 (0.70) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| Naphthazalin SCHEMBL29353283 | 0.85 | TXNRD1 (1.00) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| Naphthazalin SCHEMBL149279 | 0.85 | TXNRD1 (1.00) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| Naphthazalin SCHEMBL27700955 | 0.85 | TXNRD1 (1.00) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| Naphthazalin SCHEMBL6122890 | 0.83 | TXNRD1 (0.94) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| Naphthazalin SCHEMBL21403377 | 0.83 | TXNRD1 (0.94) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| SCHEMBL3896954 | 0.76 | CSNK2A2 (0.54) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| SCHEMBL10401666 | 0.74 | TXNRD1 (0.76) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| SCHEMBL2182692 | 0.73 | AURKA (0.73) | TXNRD1AURKACDC25BAURKBTXNRD3 | |
| SCHEMBL17265619 | 0.73 | AURKA (0.73) | TXNRD1AURKACDC25BAURKBTXNRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |